차병현
줄기세포 생물학, 줄기세포공학, 조직공학, 재생의학
학력
2007 강원대학교 동물생명과학대학 학부
2009 강원대학교 동물생명과학대학 석사
2013 차의과학대학교 의생명과학대학 박사
주요경력
2018~2021 Postdoctoral Research Associate at Div. of Cardiothoracic Surgery, Dept. of Surgery, University of Arizona
2016~2018 Research Professor at Dept. of Biomedical Science, CHA University
2014~2016 Postdoctoral Fellow at Dept. of Biomedical Science, Harvard Medical University / Wyss institute at Harvard University
주요연구실적
학위논문
- Development of therapeutic chondrocytes by delivery of chondrogenesis and antisenescence related genes. Ph.D. in Biomedical Science. CHA University
- Altere DNA methylation of repeat sequences and exprssion of placenta-related genes (Cdx2 and GATA6) in cloned porcine development. M.S in Animal Science. Kangwon National University
교육 및 연구경력
국내·외 특허등록 및 출원
- Inventor: S-H. Lee, J-S. Kim, B. Choi, I. B, Han, B-H. Cha, G-H. Lee. “SORTING METHOD OF MESENCHYMAL STEM CELL DERIVED FROM PLURIPOTENT STEM CELL” (PCT number: WO2018074826A1; Apr 26, 2018
- Inventor: S-H. Lee, J-S. Kim, B. Choi, B-H. Cha, G-H. Lee. “만능줄기세포로부터 유래된 중간엽줄기세포를 선별하는 방법” (Korea patent registration number: 10-1798217; Nov 09, 2017)
- Inventor: S-H. Lee, J. C. Ahn, B-H. Cha, B. J. Kim, J-S. Kim, S. K. Park, H-N. Lee. “퇴행성 관절염의 예방 또는 치료용 약학 조성물” (Korea public patent number: 10-2017-0025681; Mar 08, 2017)
- Inventor: S-H. Lee, S. Ashraf, S. Park, B-H. Cha, J. C. Ahn. “Rheb 유전자를 이용한 연골세포의 노화 및 탈분화 억제 방법” (Korea patent registration number: 1016766090000; Nov 11, 2016).
- Inventor: S-H. Lee, J. C. Ahn, B-H. Cha, J-S. Kim, S. K. Park, H-N. Lee. “탈분화된 연골세포의 정상 연골세포로의 전환 방법” (Korea patent registration number: 1015817030000; Dec 24, 2015).
- Inventor: Y. Ma, B-S. Kim, S-H. Lee, B-H. Cha. “골 관련 질환 예방 및 치료를 위한 조성물(A COMPOSITION FOR PREVENTION AND TREATMENT OF BONE RELATED DISORDER)” (Korea patent registration number: 1015678670000; Nov 04, 2015).
- Inventor: Y. Ma, B-S. Kim, S-H. Lee, B-H. Cha. “A COMPOSITION FOR PREVENTION AND TREATMENT OF BONE RELATED DISORDER” (PCT number: WO2014021694A1; Nov, 2014).
- Inventor: S-H. Lee, J. C. Ahn, B-H. Cha, H. J. Cha. “연골세포의 탈분화 억제 방법(Methods for inhibiting dedifferentiation of chondrocytes)” (Korea patent registration number: 1013224300000; Oct 21, 2013).
- Inventor: S-H. Lee, B-H. Cha, J-S. Kim, S-W. Kang, S. K. Park, I. B. Han, D. A. Shin. “타우로우루소데옥시콜릭산을 이용한 성체줄기세포의 연골세포 또는 골세포로의 분화방법” (Korea patent registration number: 1012809110000; Jun 26, 2013).
- Inventor: S-H. Lee, S-W. Kang, J-S. Kim, B-H. Cha. “METHOD FOR MANUFACTURING TISSUE-RECONSTRUCTION SCAFFOLD USING BIODEGRADABLE POLYMER HAVING THERMAL STABILITY” (PCT number: WO2011099736A3; Jan, 2012).
- Inventor: S-H. Lee, S-W. Kang, J-S. Kim, B-H. Cha. “열적 안정성을 갖는 생분해성 고분자를 이용한 조직재생용 지지체의 제조방법” (Korea patent registration number: 1011060180000; Jan 09, 2012).
국내·외 미디어소개
- · Tauroursodeoxycholic acid enhances osteogenic differentiation of bone marrow-derived mesenchymal stem cells and bone regeneration. Bone 2016 83: 73–81. (Highlighted by Mesenchymal Cell News (Issued from STEMCELL Technologies Inc. (Posted on Oct 27, 2015)); http://www.mesenchymalcellnews.com/issue/volume-7-42-oct-27/)
- · Engineering photocrosslinkable bicomponent hydrogel constructs for creating 3D vascularized bone. Advanced Healthcare Materials 2017 6(10): doi: 10.1002/adhm.201601122. (Highlighted by Advanced Science News (Posted on April 11, 2017); http://www.advancedsciencenews.com/?p=41694)
- · Bioprinted 3D vascularized tissue model for drug toxicity analysis. Biomicrofluidics 2017 11(4):044109. (Highlighted by 3D Printing Industry (Posted on August 14, 2017); https://3dprintingindustry.com/news/harvard-mit-liver-chipnarrows-gap-vitro-vivo-drug-tests-120088/)
- · Integrin-mediated interactions control macrophage polarization in 3D hydrogels. Advanced Healthcare Materials 2017 6(21):doi:10.1002/adhm.201700289. (Highlighted by Advanced Science News (Posted on September 14, 2017); http://www.advancedsciencenews.com/read-featuring-braintherapy-bioink-3d-hydrogels/)
그 외
전공 Biomedical Science, Molecular biotechnology, Developmental Biology