의생명시스템과학과

KANGWON NATIONAL UNIVERSITY

학력

2007 강원대학교 동물생명과학대학 학부
2009 강원대학교 동물생명과학대학 석사
2013 차의과학대학교 의생명과학대학 박사

주요경력

2018~2021 Postdoctoral Research Associate at Div. of Cardiothoracic Surgery, Dept. of Surgery, University of Arizona
2016~2018 Research Professor at Dept. of Biomedical Science, CHA University
2014~2016 Postdoctoral Fellow at Dept. of Biomedical Science, Harvard Medical University / Wyss institute at Harvard University

주요연구실적

학위논문
Development of therapeutic chondrocytes by delivery of chondrogenesis and antisenescence related genes. Ph.D. in Biomedical Science. CHA University
Altere DNA methylation of repeat sequences and exprssion of placenta-related genes (Cdx2 and GATA6) in cloned porcine development. M.S in Animal Science. Kangwon National University

교육 및 연구경력

국내·외 특허등록 및 출원
Inventor: S-H. Lee, J-S. Kim, B. Choi, I. B, Han, B-H. Cha, G-H. Lee. “SORTING METHOD OF MESENCHYMAL STEM CELL DERIVED FROM PLURIPOTENT STEM CELL” (PCT number: WO2018074826A1; Apr 26, 2018
Inventor: S-H. Lee, J-S. Kim, B. Choi, B-H. Cha, G-H. Lee. “만능줄기세포로부터 유래된 중간엽줄기세포를 선별하는 방법” (Korea patent registration number: 10-1798217; Nov 09, 2017)
Inventor: S-H. Lee, J. C. Ahn, B-H. Cha, B. J. Kim, J-S. Kim, S. K. Park, H-N. Lee. “퇴행성 관절염의 예방 또는 치료용 약학 조성물” (Korea public patent number: 10-2017-0025681; Mar 08, 2017)
Inventor: S-H. Lee, S. Ashraf, S. Park, B-H. Cha, J. C. Ahn. “Rheb 유전자를 이용한 연골세포의 노화 및 탈분화 억제 방법” (Korea patent registration number: 1016766090000; Nov 11, 2016).
Inventor: S-H. Lee, J. C. Ahn, B-H. Cha, J-S. Kim, S. K. Park, H-N. Lee. “탈분화된 연골세포의 정상 연골세포로의 전환 방법” (Korea patent registration number: 1015817030000; Dec 24, 2015).
Inventor: Y. Ma, B-S. Kim, S-H. Lee, B-H. Cha. “골 관련 질환 예방 및 치료를 위한 조성물(A COMPOSITION FOR PREVENTION AND TREATMENT OF BONE RELATED DISORDER)” (Korea patent registration number: 1015678670000; Nov 04, 2015).
Inventor: Y. Ma, B-S. Kim, S-H. Lee, B-H. Cha. “A COMPOSITION FOR PREVENTION AND TREATMENT OF BONE RELATED DISORDER” (PCT number: WO2014021694A1; Nov, 2014).
Inventor: S-H. Lee, J. C. Ahn, B-H. Cha, H. J. Cha. “연골세포의 탈분화 억제 방법(Methods for inhibiting dedifferentiation of chondrocytes)” (Korea patent registration number: 1013224300000; Oct 21, 2013).
Inventor: S-H. Lee, B-H. Cha, J-S. Kim, S-W. Kang, S. K. Park, I. B. Han, D. A. Shin. “타우로우루소데옥시콜릭산을 이용한 성체줄기세포의 연골세포 또는 골세포로의 분화방법” (Korea patent registration number: 1012809110000; Jun 26, 2013).
Inventor: S-H. Lee, S-W. Kang, J-S. Kim, B-H. Cha. “METHOD FOR MANUFACTURING TISSUE-RECONSTRUCTION SCAFFOLD USING BIODEGRADABLE POLYMER HAVING THERMAL STABILITY” (PCT number: WO2011099736A3; Jan, 2012).
Inventor: S-H. Lee, S-W. Kang, J-S. Kim, B-H. Cha. “열적 안정성을 갖는 생분해성 고분자를 이용한 조직재생용 지지체의 제조방법” (Korea patent registration number: 1011060180000; Jan 09, 2012).
  
국내·외 미디어소개
· Tauroursodeoxycholic acid enhances osteogenic differentiation of bone marrow-derived mesenchymal stem cells and bone regeneration. Bone 2016 83: 73–81. (Highlighted by Mesenchymal Cell News (Issued from STEMCELL Technologies Inc. (Posted on Oct 27, 2015)); http://www.mesenchymalcellnews.com/issue/volume-7-42-oct-27/)



· Engineering photocrosslinkable bicomponent hydrogel constructs for creating 3D vascularized bone. Advanced Healthcare Materials 2017 6(10): doi: 10.1002/adhm.201601122. (Highlighted by Advanced Science News (Posted on April 11, 2017); http://www.advancedsciencenews.com/?p=41694)


· Bioprinted 3D vascularized tissue model for drug toxicity analysis. Biomicrofluidics 2017 11(4):044109. (Highlighted by 3D Printing Industry (Posted on August 14, 2017); https://3dprintingindustry.com/news/harvard-mit-liver-chipnarrows-gap-vitro-vivo-drug-tests-120088/)


· Integrin-mediated interactions control macrophage polarization in 3D hydrogels. Advanced Healthcare Materials 2017 6(21):doi:10.1002/adhm.201700289. (Highlighted by Advanced Science News (Posted on September 14, 2017); http://www.advancedsciencenews.com/read-featuring-braintherapy-bioink-3d-hydrogels/)

  

그 외

전공  Biomedical Science, Molecular biotechnology, Developmental Biology